Anticonvulsant hypersensitivity syndrome secondary to lamotrigine mimicking a septic episode.
نویسندگان
چکیده
Dear Editor, Anticonvulsant hypersensitivity syndrome consists of the hallmark features of fever, rash, and lymphadenopathy and multiorgan involvement. We report a case of lamotrigine hypersensitivity that was diffi cult to diagnose because of comorbid systemic lupus eythrmatosus (SLE), and the presence of clinical features mimicking sepsis due to a zoonosis. The syndrome resolved with the discontinuation of the medication. Timely recognition of this rare but potentially fatal drug reaction is important.
منابع مشابه
Anticonvulsant hypersensitivity syndrome
Hypersensitivity to anticonvulsant drugs have been reported many times. But anticonvulsant hypersensitivity syndrome (AHS) is a potentially fatal drug reaction with cutaneous and systemic reaction to the arene oxide-producing anticonvulsants, phenytoin, carbamazepine, and Phenobarbital sodium. The hall-mark features of this syndrome are: Fever, rash and lymphadenopathy. The epoxide hydrolase en...
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Anticonvulsant hypersensitivity syndrome (AHS) is a rare, but severe and potentially fatal, adverse reaction that occurs in patients who are treated with commonly used older anticonvulsant drugs (phenytoin, carbamazepine and phenobarbital) and/or with some newer agents (lamotrigine). Paediatric patients are at an increased risk for the development of AHS for the higher incidence of seizure diso...
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عنوان ژورنال:
- Annals of the Academy of Medicine, Singapore
دوره 40 9 شماره
صفحات -
تاریخ انتشار 2011